Lifelong vaccination strategy as a tool against pandemics in Hungary / Élethosszan át tartó oltási stratégia mint eszköz a pandémiák elleni védekezésben Magyarországon.

Összefoglaló. Különbözo tényezok következtében az új és újra felbukkanó fertozo betegségek megjelenésére a 21. században egyre nagyobb az esély, ezzel párhuzamosan a pandémiák kialakulása is nagyobb valószínuségu. A 2019-ben felbukkant COVID-19-járvány azt is közvetíti számunkra, hogy egyes új és újra jelentkezo fertozo betegségek - az eredményes intézkedések elmaradása, késlekedése esetén - gyorsan terjedhetnek. A fertozo betegségek elleni harc egyik fo eszköze a védooltás segítségével történo immunizáció. A jelen tanulmány célja bemutatni a védooltások elonyeit, fókuszba helyezve az elöregedo társadalomban az élethosszan tartó immunizációs stratégiának a személyes egészségre ható, közegészségügyi, gazdasági, valamint társadalmi érdekeit. Az oltás elonyeinek minél nagyobb fokú kihasználásához egy élethosszan tartó immunizációs stratégia felállítása javasolható, amelynek aspektusait és gyakorlatba ültetésének lehetséges lépéseit foglaltuk össze közleményünkben. Orv Hetil. 2022; 163(14): 535-543. Summary. Due to various factors, the chances of infectious disease emergence or re-emergence have increased in the 21st century, thus, the likelihood of new emerging pandemics has also increased. The COVID-19 pandemic, which appeared in 2019, has highlighted that certain new and re-emerging infectious diseases - in the case of lack or delay in effective measures - can spread very rapidly. The main tool for the fight against infectious diseases is immunization through vaccination. While focusing on the personal health, public health, economic and societal benefits of a lifelong immunization strategy, especially in light of the aging society, the goal of this paper is to present the benefits of vaccines. In order to increase the added value of vaccinations it is recommended to create a lifelong immunization strategy. Our paper summarizes the relevant aspects of such a strategy, highlighting potential practical steps towards implementation. Orv Hetil. 2022; 163(14): 535-543.

Kétoldali Parsonage-Turner-szindróma COVID-19-vakcinációt követoen.

Parsonage-Turner syndrome (PTS; neuralgic amyotrophy) is a generally unilateral neuritis with sudden onset, severe shoulder or upper arm pain. Although the intense pain is usually self-limiting, two-thirds of patients experience progressive motor weakness, narrowed range of motion, reflex changes, dysesthesias and chronic neuropathic pain in the shoulder girdle musculature and proximal upper limb muscles. The aetiology is unclear, in addition to some idiopathic cases the most common triggers of PTS are surgery, trauma, infection or vaccination. It is reported after SARS-CoV-2 infection, and unilateral PTS has been described in some cases following different types of COVID-19 vaccines. We are currently presenting the case of a middle-aged woman who developed partial neuralgic amyotrophy on the right shoulder one month after receiving the second dose of the BNT162b2 COVID-19 mRNA vaccine (Pfizer-BioNTech), and seven months later the symptoms appeared in the contralateral upper limb. The diagnosis of PTS was also confirmed by magnetic resonance and electrodiagnostic examination. The PTS is not an uncommon condition, but in the absence of knowledge it is rarely thought of. The purpose of this report is to draw attention to the possibility of PTS in shoulder or upper arm pain following both SARS-CoV-2 infection and COVID-19 vaccination, as early diagnosis and adequate therapy may help to shorten the course of the disease. Orv Hetil. 2022; 163(27): 1055-1060.

Az influenza mint kardiológiai rizikótényezo és a vakcináció szerepe a kockázat csökkentésében.

The different types of cardiovascular diseases, including coronary heart disease, cardiac arrhythmias and heart failure are highly prevalent in the society. Cardiovascular diseases are the leading cause of mortality. Although the influenza is forced out from the mainstream of thinking nowadays because of the ongoing SARS-CoV-2 pandemic, it still has its serious epidemiological significance. The seasonal influenza epidemic often contributes to mortality mainly, but not exclusively among old, multi-morbid patients. There are a vast number of scientific publications and evidence which prove and emphasize the synergic health-destroying and mortality-increasing effect of co-existing cardiovascular disease and influenza. Moreover, the beneficial effect of vaccination against influenza infection and its major role in prevention is also well documented. The SARS-CoV-2 pandemic enforces the importance of influenza vaccination because both viruses can lead to severe or often fatal disease, especially among old and frail patients. In addition, the younger population can be far more vulnerable against the novel coronavirus in the case of a co-existing influenza infection. International guidelines recommend influenza vaccination for patients having heart disease, like for other high-risk populations. Despite the nationally reimbursed, cost-free vaccines, the influenza vaccination rate of the society is still low not just in Hungary but also internationally. The authors review the effect of influenza infection on heart diseases, and draw attention to the role of influenza vaccination in decreasing cardiovascular morbidity and mortality. Orv Hetil. 2022; 163(40): 1585-1596.

A COVID-19 elleni oltóanyagot elutasítók az aktív korú felnott magyar lakosság körében 2021 decemberében.

INTRODUCTION: In 2021, vaccines against COVID-19 became widely available in Hungary, but a part of the population refuses to be vaccinated, which hinders the control of the pandemic. OBJECTIVE: To explore the sociodemographic characteristics of the Hungarian vaccination-refusing population and to preliminarily explore the reasons behind their refusal. METHODS: In December 2021, survey data were collected online using quota-sampling among the Hungarian population aged 18-65 years with internet access. Sociodemographic variables, individual variables, and reasons for refusal were asked. 1905 completed questionnaires were included in this analysis. After variable selection using LASSO regression, binary logistic regression was used to identify the influencing variables. Reasons for rejection were examined both descriptively and using hierarchical classification. RESULTS: Respondents with lower income, lower education, females, younger age, people living in smaller municipalities and who perceived their own health as better were more likely to refuse vaccination. No similar associations were found with marital status, household size, life satisfaction and loneliness. Distrust of vaccination, safety concerns (especially side effects) and efficacy concerns are the main reasons for refusal, and to a lesser extent, the belief of immunity. CONCLUSIONS: Vaccination refusal is higher in vulnerable groups, which further increases their health risks. Alongside a well-designed health communication campaign, restoring trust in scientific and health institutions, transparent communication and a community-based approach appear to be important to increase vaccination uptake in Hungary. Orv Hetil. 2022; 163(29): 1135-1143.